NAD+ In skincare: The Possible Solution to Anti-Aging
By: Shahara Lum
NAD+, short for Nicotinamide adenine dinucleotide, is becoming increasingly popular in the skincare industry due to its potential anti-aging and skin health benefits. This essential coenzyme is present in all living cells and plays an important role in many metabolic processes, including DNA repair, energy production, and cell signaling. The expanding research on NAD+ suggests that it can be a powerful ingredient in advanced skincare products, providing skin rejuvenation and protection.
Why is NAD+ so popular
NAD+ is becoming increasingly popular because of its connection to anti-aging. According to research, our NAD+ levels naturally decline with age, which can lead to metabolic and mitochondrial dysfunction. This decline can lead to metabolic and mitochondrial dysfunction associated with various aging symptoms and diseases. From neurodegeneration to cardiovascular diseases and even decreased skin health, the effects of this decline can be significant. However, recent research has shown that NAD+ can reverse these declines, making it a major area of research and capturing the public’s attention as a possible “anti-aging” molecule. [1]
NAD+ has also been found to have potential benefits for overall health and wellness. Some research suggests that boosting NAD+ levels may improve cognitive function, increase endurance, and even extend lifespan in some animal studies. To increase NAD+ levels, there are a few different approaches. One is to consume foods rich in NAD+ precursors, such as milk, fish, and yeast. Another is to take supplements that contain NAD+ or its precursors, such as nicotinamide riboside or nicotinamide mononucleotide (NMN). Finally, some skincare products now contain NAD+ or NAD+ can help support skin health from the outside in. [2]
Topical Application of NAD+
Recent research has shown that NAD+ could be a promising ingredient in skincare products. When applied topically, NAD+ can penetrate the outer layers of the skin and provide targeted benefits. It has been found to increase energy levels in skin cells, which can promote better cell turnover and renewal. Moreover, NAD+ is believed to stimulate collagen production, essential for maintaining the skin’s elasticity and firmness.
Although NAD+ can penetrate the skin when correctly formulated, it quickly converts to niacinamide, a popular ingredient already used by many skincare brands. Niacinamide is known to slow down key aging processes, and some studies suggest that it may increase NAD+ levels in the skin, improving lines, wrinkles, and pigmentation disorders. However, delivering stable NAD+ in topical form is challenging, and many skincare products containing NAD+ precursors are now available.
One of the challenges in incorporating NAD+ into skincare formulations is ensuring its stability and absorption. Fortunately, advances in skincare technology have led to the development of innovative delivery systems, such as encapsulation and liposomal delivery. These delivery systems help protect NAD+ from degradation and improve its penetration into the deeper layers of the skin, making it more effective in promoting healthy and youthful-looking skin.
NAD+ and Antioxidant Synergy
Studies have shown that NAD+ also works in synergy with other antioxidants to protect skin cells from oxidative stress which can cause aging and other skin damage. One of the most significant benefits of NAD+ is its role in the function of sirtuins, a group of proteins that regulate cellular health and longevity. Sirtuins help in cellular repair and have anti-inflammatory properties that are beneficial for maintaining skin health and appearance.
The combination of NAD+ with other antioxidants such as vitamin C, resveratrol, and coenzyme Q10 in skincare formulations can provide comprehensive protection against environmental damage and boost cellular energy. These antioxidants protect skin cells from the harmful effects of UV rays, pollution, and other environmental stressors that can cause damage and accelerate the aging process.
Best skin products with NAD+
When searching for skincare products that contain NAD+ or its by-products, you should pay attention to the product’s formulation. This will ensure that you are getting the most effective and safe product for your skin. Some of the top-rated skincare products that incorporate NAD+ or its derivatives include serums, creams, and moisturizers.
- Eternal Platinum NAD Face cream
- SKINN Deep Wrinkle Facial Serum
- HPN NAD+ Booster
- Neurogan Cellular Repair Serum
- Elysium Basis NAD+ Supplement
- Quicksilver Scientific Liposomal NAD+ Gold
- Codeage Eternal Platinum NAD Serum
- PRIMONUTRA Renew NMN Supplement
- Aurora Nutrascience Mega-Liposomal NAD+/Resveratrol
- TRU NIAGEN NAD+ Boosting Supplement
- Paula’s Choice Super Antioxidant Serum
- PEACH & LILY Glass Skin Refining Serum
- Olay Regenerist Brightening Vitamin C Face Moisturizer
- Paula’s Choice Phytoestrogen Elasticity Renewal Serum
- Murad Cellular Hydration Repair Serum
Should you add NAD+ products to your skin routine?
While it is a personal choice, you should approach it with caution because there is scientific evidence supporting its topical use is not yet solid enough. While NAD might be considered more of a trend than a proven necessity, it is worth considering if you are looking for a new ingredient to add to your skincare routine, especially if you are already using well-established ingredients like vitamin C, vitamin A, and AHAs.
If you are looking to increase your NAD+ intake through your diet, consider eating foods that are rich in amino acids that are also precursors to NAD+. Foods like broccoli, cabbage, avocados, steamed fish, and peanuts are great options. Additionally, engaging in high-intensity interval training (HIIT) has been found to boost the body’s NAD+ production pathway. A recent study found that adults who exercised frequently and intensely had NAD+ levels similar to those of young adults, indicating that exercise can help maintain healthy NAD+ levels as we age.
The future of NAD+
As scientific research on NAD+ in skincare continues to advance, we can expect to see more innovative and effective products emerge in the market. However, consumers and professionals need to stay informed about the safety and usefulness of these products. Ongoing research is also needed to determine the optimal concentrations and combinations of NAD+ with other ingredients that can maximize the benefits for skin health. As we delve deeper into its potential, it could soon become a go-to ingredient in anti-aging skincare routines, helping people maintain healthy and youthful skin for longer.
Works cited
[1]https://www.womenshealthmag.com/uk/beauty/skin/a46504210/na
d-skincare/#
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512238/
[3] https://www.usmagazine.com/shop-with-us/news/nad-skincare-
supplements-amazon/
[4] https://cnalifestyle.channelnewsasia.com/style-beauty/nad-new-
hero-anti-ageing-ingredient-384331
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